Molecule P57

Author: hoodiagirl, 06 12th, 2008

Molecule P57

The Molecule P57.

In 1937, a Dutch anthropologist studying the San people noted that they used Hoodia to suppress appetite. But it wasn’t until 1963, when scientists at the Council for Scientific and Industrial Research (CSIR), South Africa’s national laboratory, began studying Hoodia. Initial results were promising – lab animals lost weight after eating Hoodia Gordonii.                                                                                                                                                                                        After 30 years of research, the South African scientists at CSIR isolated the active ingredient in Hoodia, and obtained a patent on the molecule in 1995. It is a steroidal glycoside, which they named P57. The South African government then licensed the patent to a British firm named Phytopharm.
Then, Phytopharm licensed the patent to American drug giant, Pfizer. The intent was to use the molecule, P57, as a base, to mass-create an artificial drug to meet the demands of millions of people. After three years of investigation, Pfizer pulled out of the deal, saying it would be too expensive to ever bring to market
In December of 2004, Phytopharm licensed to Unilever, who has promised to bring this man-made drug to market.
It remains to be seen if a weight loss drug utilizing P57 will ever be realized.


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